Elemental Analysis of Nasal Epithelial Lining Fluid in COPD Patients
نویسندگان
چکیده
منابع مشابه
Fosfomycin concentrations in epithelial lining fluid in weaning piglets.
Respiratory diseases are one of the most important problems in modern intensive swine production (Gardner and Hird, 1990). These diseases are a common cause of morbidity and mortality in weaning pigs (Gardner and Hird, 1990; Galina et al., 1994; Dos̆en et al., 2007). The concentrations of antibiotics in epithelial lining fluid (ELF) reflect the antimicrobial activity for extracellular pathogens ...
متن کاملNormal alveolar epithelial lining fluid contains high levels of glutathione.
The epithelial cells on the alveolar surface of the human lower respiratory tract are vulnerable to toxic oxidants derived from inhaled pollutants or inflammatory cells. Although these lung cells have intracellular antioxidants, these defenses may be insufficient to protect the epithelial surface against oxidants present at the alveolar surface. This study demonstrates that the epithelial linin...
متن کاملContinuous monitoring of the bronchial epithelial lining fluid by microdialysis
BACKGROUND Contents of the epithelial lining fluid (ELF) of the bronchi are of central interest in lung diseases, acute lung injury and pharmacology. The most commonly used technique broncheoalveolar lavage is invasive and may cause lung injury. Microdialysis (MD) is a method for continuous sampling of extracellular molecules in the immediate surroundings of the catheter. Urea is used as an end...
متن کاملEpithelial lining fluid solute concentrations in chronic obstructive lung disease patients and normal subjects.
The exhaled breath condensate (EBC) method represents a new, noninvasive way to detect inflammatory and metabolic markers in the fluid that covers the airways [epithelial lining fluid (ELF)]. However, respiratory droplets represent only a very small and variable fraction of the EBC, most (approximately 99.99%) of which is water vapor. Our objective was to show that ELF concentrations could be c...
متن کاملPenetration of meropenem into epithelial lining fluid of patients with ventilator-associated pneumonia.
Antibiotic penetration to the infection site is critical for obtaining a good clinical outcome in patients with ventilator-associated pneumonia (VAP). Surprisingly few studies have quantified the penetration of β-lactam agents into the lung, as measured by the ratio of area under the concentration-time curve (AUC) in epithelial lining fluid (ELF) to AUC in plasma (AUC(ELF)/AUC(plasma) ratio). T...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Environmental Epidemiology
سال: 2019
ISSN: 2474-7882
DOI: 10.1097/01.ee9.0000609644.80593.3e